| 摘要 |
<p>NEW MATERIAL:An antibiotic AM-5344-A2 having the following physico- chemical properties: Elementary analysis (%): C, 63,87; H, 3.96; N, 2.29. [alpha]D<20>=-214 deg. (C=0.25, CHCl3). Melting point >290 deg.C. Soluble in chloroform, slightly soluble in acetone, ethyl acetate, benzene and lower alcohols, and insoluble in water, etc. USE:An antimicrobial and antiprotozoal agent against Gram-positive bacteria, anaerobes and trichomonal protozoans. PROCESS:A microorganism of the genus Streptomyces, e.g. Streptomyces sp. AM-5344 (FERM-P No.67) is clutivated at a pH of 6-7 and 25-30 deg.C for 50- 100hr preferably by the spinner culture method with aeration, and the aimed antibiotic is then separated and purified.</p> |
