摘要 |
Manufacture of orthomethylated phenol compounds by the reaction of phenol compounds having a hydrogen atom at the ortho position and methanol is accomplished advantageously by a method which effects the reaction by use of a catalyst comprising (A) iron oxide, (B) indium oxide, and (C) at least one member selected from the group consisting of chromium oxide and silicon oxide. According to this method, the reaction permits the orthomethylated phenol compound to be produced in high yields for a long time because of the catalyst's excellent activity-retaining property. Since the ortho-position selectivity and the utilization ratio of methanol are high and, consequently, the utilization efficiency of raw materials is high, the method of this invention produces the orthomethylated phenol compound with high efficiency from the phenol compounds. |