N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them.

摘要

The N-acylpeptide compounds are represented by the general formula:-
<CHEM>
wherein R<1> and R<2> are each alkyl or alkenyl;
R<3> is hydrogen, lower alkyl, hydroxy(lower)alkyl, heterocyclic(lower)alkyl or ar(lower)alkyl, wherein the aryl moiety may have hydroxy or protected hydroxy;
R<4> is carboxy, esterified carboxy, carboxy(lower)alkyl or esterified carboxy(lower)alkyl;
X is a bond or lower alkylene;
Y is lower alkylene or lower alkylidene and n is 0 or 1; and including their pharmaceutically acceptable salts.
<??>These compounds are useful as therapeutic agents in the treatment of immune-complex or autoimmune diseases.