发明名称 |
Dihydro-dibenzoxepines-thiepines and -morphanthridones, compositions and use |
摘要 |
The invention relates to diuretic dihydro-dibenzoxepines-thiepines and -morphanthridones of the formula <IMAGE> wherein R is <IMAGE> where R4 is a hydrogen or an alkyl; R1 is hydrogen or alkyl; R2 and R3 are the same or different and are hydrogen, alkyl or R2 and R3 are fused to form a pyrrolidino, morpholino, piperidino or azepino ring substituent; Y is hydrogen, halogen and alkoxy, X is <IMAGE> where R4 is as defined above; m is an integer of 0 or 1; and n is an integer of 2 or 3; and the pharmaceutically acceptable acid addition salts thereof.
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申请公布号 |
US4335122(A) |
申请公布日期 |
1982.06.15 |
申请号 |
US19810225122 |
申请日期 |
1981.03.18 |
申请人 |
HOECHST-ROUSSEL PHARMACEUTICALS INC. |
发明人 |
MCFADDEN, ARTHUR R.;AULTZ, DANIEL E. |
分类号 |
C07D223/20;C07D313/12;C07D337/12;(IPC1-7):A61K31/33;A61K31/55 |
主分类号 |
C07D223/20 |
代理机构 |
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主权项 |
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地址 |
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