| 摘要 |
PURPOSE:To obtain an inspection reagent by fixing an immunoactive substance with an amino group to a copolymer, having a diameter of 0.03-10mum, of glycidyl acrylate or glycidyl methacrylat and a water-soluble monomer with a carbon unsaturated double bond. CONSTITUTION:It is possible to vary within a range between 95:5 and 5:95 in mol ratio the ratio of the sum of glycidyl acrylate and glycidyl methacrylate in any ratio and the sum of water-soluble monomers such as 2-oxyethyl acrylate, 2-oxyethyl methacrylate or the like. An immunoactive substance is fixed on a carrier particle by means of the covalent bond produced through the reaction between the amino group of the substance and the free epoxy group on the particle surface. The immunoactive substance-fixed particle thus produced is stable to a specimen body fluid, so that a nonspecific agglutination hardly takes place and there is no nonspecific adhesion to cells. |
