Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them.

摘要

New derivatives of general formula (I) in which R is a 2-(2-amino-4-thiazolyl)acetyl, 2-(2-amino-4-thiazolyl)-2-methoxyiminoacetyl radical or 2-(2-amino-4- thiazolyl)-2-carboxyalkoxyiminoacetyl radical [in which the carboxyalkyl part may be denoted by the general formula (II) in which R' and R'', which are identical or different, denote hydrogen atoms or alkyl radicals containing 1 to 4 carbon atoms, or together form an alkylene radical containing 2 or 3 carbon atoms], an N-(2,3-dioxo-4-ethylpiperazinylcarbonyl)-D- alpha -p-hydroxyphenylglycyl or N-[(4-hydroxy-6-methyl-3-pyridyl)carbonyl]-D- alpha -p-hydroxyphenylglycyl radical and Het is a variously substituted 5,6-dioxo-1,2,4-triazin-3-yl radical, and their salts, their preparation and the pharmaceutical compositions which contain them. <IMAGE>