发明名称 Carboxamidine derivatives and hypoglycemical use
摘要 A compound of formula (II) or a pharmaceutically acceptable acid addition salt thereof <IMAGE> (II) wherein R1, R2, R3 and R4 are the same or different and each represents C1-6 alkyl; R5 represents hydrogen or C1-6 alkyl; R6 represents C1-6 alkyl, phenyl optionally substituted with up to 3 groups selected from halogen, C1-6 alkyl, and C1-6 alkoxy; or benzyl optionally substituted with up to 3 groups selected from halogen, C1-6 alkyl and C1-6 alkoxy; or R5 and R6 together represent the remaining members of a 5- or 6-membered ring optionally containing an oxygen, sulphur or additional nitrogen atom and being optionally substituted with C1-6 alkyl, carboxy or C1-6 alkoxycarbonyl; and R7 represents C1-6 alkyl, phenyl optionally substituted with up to 3 groups selected from halogen, C1-6 alkyl and C1-6 alkoxy; or benzyl optionally substituted with up to 3 groups selected from halogen, C1-6 alkyl and C1-6 alkoxy, has useful hypoglycaemic activity.
申请公布号 US4333929(A) 申请公布日期 1982.06.08
申请号 US19810226180 申请日期 1981.01.19
申请人 BEECHAM GROUP LIMITED 发明人 CANTELLO, BARRIE C. C.
分类号 A61K31/155;A61P3/08;A61P3/10;C07C67/00;C07C239/00;C07C279/26;C07C281/16;C07D295/215;(IPC1-7):A61K31/15;A61K31/54;C07C129/00;C07D279/10 主分类号 A61K31/155
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