摘要 |
<p>A process for the preparation of 3- exomethylene cepham sulphoxide of formula (I): <IMAGE> wherein R and R<1> are independently hydrogen or acyl and where R<2> is hydrogen or an ester protecting group, which process comprises treating a compound of formula (II): <IMAGE> where R, R<1> and R<2> are as previously defined and where X is bromine or iodine, with a mercury salt containing a non-nucleophilic anion.</p> |