发明名称 WATER HOLDING BASE AND PREPARATION THEREOF
摘要 PURPOSE:To enable to prepare water holding base with excellent oleophilicity and water holding ability, by reacting a secific long-chain glycol or a long-chain oxide having a straight-chain hydrocarbon group with isostearic acid by using a specific catalyst. CONSTITUTION:Equimolar isostearic acid is added to a 14-18C straight-chain alkylene 1,2-glycol or a 14-18C straight-chain alkylene 1,2-oxide and, by using an alkali metal salt such as a K, Na or Li salt of an 8C or higher medium or higher fatty acid such as octanoic acid, decanoic acid or myristic acid, reacted under heating at 150-190 deg.C for about 4hr to prepare a water holding base comprising a hydroxyalkyl isostearate shown by formulas I or II. The resulting water holding base has oleophilicity and water holding ability similr to that of lanolin and has excellent characteristics free from a fear of skin sensitization. In formulae I and II, R1 is a 12-16C straight-chain alkyl group and R2 is an isostearic acid residue.
申请公布号 JPS5784729(A) 申请公布日期 1982.05.27
申请号 JP19800159917 申请日期 1980.11.13
申请人 MATSUMOTO SEIYAKU KOGYO KK 发明人 SUGIYAMA IWAKICHI;WATANABE AKIHISA;SHIKII KUNIO
分类号 C07C67/08;A61K8/30;A61K8/34;A61K8/36;A61K8/37;A61K8/49;A61K9/06;A61K47/00;A61K47/14;A61Q19/00;B01F17/34;B01F17/38;B01J31/00;B01J31/04;C07B61/00;C07C69/28 主分类号 C07C67/08
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