发明名称 Dithioacyldihydropyrazole carboxylic acid derivatives
摘要 Compounds having the formula <IMAGE> and <IMAGE> wherein: R1 is hydrogen, alkyl, aryl or arylalkyl; R2 is hydrogen and R3 is hydrogen, hydroxy, alkoxy or halogen, or together R2 and R3 can be =Q or -X-(CH2)t-X- wherein X is oxygen or sulfur and t is 2 or 3; R4 is hydrogen or alkyl; R5 is hydrogen, alkyl or trifluoromethyl; R6 is alkyl of 1 to 20 carbon atoms, aryl, arylalkyl or a 5- or 6-membered heterocyclic group having 1 to 2 nitrogen, sulfur or oxygen atoms in the ring; R7 is aryl; m is 0, 1 or 2; and n is 1 or 2 have useful hypotensive activity.
申请公布号 US4331806(A) 申请公布日期 1982.05.25
申请号 US19800214152 申请日期 1980.12.08
申请人 E. R. SQUIBB & SONS, INC. 发明人 HAUGWITZ, RUDIGER D.
分类号 A61K31/38;A61K31/40;A61K31/415;C07D207/16;C07D231/06;(IPC1-7):C07D401/12;C07D403/12;C07D405/12;C07D413/12 主分类号 A61K31/38
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