PENICILLANIC ACID PENICILLANOYLOXYMETHYL- 1,1,1',1'-TETRAOXIDE AND MANUFACTURE

摘要

Penicillanoyloxymethyl penicillanate 1,1,1 min ,1 min -tetraoxide is useful for enhancing the activity of betalactam antibiotics in the treatment of bacterial infections in mammalian subjects. A pharmaceutical composition comprising a suspension of penicillanoyloxymethyl penicillanate 1,1,1 min 1 min -tetraoxide in water is disclosed which is particularly valuable for use with slow release forms of beta-lactam antibiotics.