发明名称 PROCEDIMIENTO PARA PREPARAR DERIVADOS AMIDICOS DE ACIDO P- ISOBUTIL-FENIL-PROPIONICO
摘要 <p>The amide derivatives of p-isobutyl-phenyl-propionic acid, having general formula <IMAGE> wherein X is the radical of a substituted amine, of the group comprising lysine, metatrifluorotoluidine, glutamic acid and aspartic acid, show a good anti- inflammatory activity, accompanied by favourable side properties. For the preparation of the compounds of the invention, the p-isobutyl-phenyl-propionic acid is chlorinated, and the chlorinated derivative is reacted with the proper substituted amine.</p>
申请公布号 ES504156(D0) 申请公布日期 1982.05.16
申请号 ES19560005041 申请日期 1981.07.21
申请人 LABORATORI PROPHIN S.P.A. 发明人
分类号 A61K31/165;A61K31/195;A61P29/00;C07C67/00;C07C231/00;C07C231/02;C07C233/12;C07C233/51;C07C237/22;(IPC1-7):07C103/52;61K31/165;07C103/76 主分类号 A61K31/165
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