发明名称 PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS POLIAZAHETERO-CICLICOS
摘要 <p>Compounds of formula I <IMAGE> (R1 and R2 represent optionally substituted aliphatic hydrocarbon radicals, optionally substituted aryl or heteroaryl each having not more than 2 rings and each being bonded directly or via alkylene or alkenylene, R3 represents hydrogen or alkyl, A represents alkylene or alkenylene having 2 to 4 carbon atoms separating the nitrogen atoms, and Z1, Z2, Z3 and Z4 represent radicals -CH= carrying any substituents of ring B, one of which members can however also be the radical -N=, wherein R1 and R2 do not both represent methyl or ethyl if R3 represents hydrogen, A represents ethenylene and ring B is unsubstituted and their salts possess diuretic and antihypertensive activity and some of them are antidiabetically active. The preparation of starting materials of formula (II> <IMAGE> is described.</p>
申请公布号 ES504736(D0) 申请公布日期 1982.05.16
申请号 ES19360005047 申请日期 1981.08.13
申请人 CIBA-GEIGY AG 发明人
分类号 A61K31/505;A61P3/06;A61P3/08;A61P7/10;A61P9/12;A61P29/00;C07D213/50;C07D233/16;C07D239/06;C07D471/14;C07D487/04;(IPC1-7):07D487/04;07D487/14;61K31/505 主分类号 A61K31/505
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