发明名称 |
Anthracycline glycosides, intermediate compounds, process for preparing both and pharmaceutical compositions. |
摘要 |
<p>Anthracycline glycosides of Formula I
<CHEM>
wherein R1 represents a hydrogen atom or a hydroxy group; R2 represents a hydrogen atom or an acyl group; R3 represents hydrogen, a methyl, amino, hydroxymethyl, aminomethyl or acylaminomethyl group; R4 represents a hydrogen atom, an amino or a hydroxy group; R3 and R4 together may represent a methylene group, and their pharmaceutically acceptable acid addition salts, together with a process of preparation are disclosed.
<??>There are also described new intermediate compounds as well as pharmaceutical compositions, which are effective against certain mammalian tumors.</p> |
申请公布号 |
EP0051279(A1) |
申请公布日期 |
1982.05.12 |
申请号 |
EP19810109243 |
申请日期 |
1981.10.29 |
申请人 |
FARMITALIA CARLO ERBA S.P.A. |
发明人 |
BARGIOTTI, ALBERTO;CASSINELLI, GIUSEPPE;PENCO, SERGIO;ARCAMONE, FEDERICO;CASAZZA, ANNA MARIA |
分类号 |
A61K31/70;A61K31/7024;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;A61P35/02;C07D309/30;C07H13/04;C07H13/06;C07H15/04;C07H15/252;(IPC1-7):07H15/24;07H13/04;61K31/70 |
主分类号 |
A61K31/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|