2-(Substituted-phenyl)-thiazole derivatives suitable for peptic ulcer treatment.

摘要

Known agents for treating peptic ulcers are either not sufficiently effective or possess undesirable side effects. These problems can be overcome by 2-(substituted-phenyl)-thiazoles having the formula (I):
<CHEM>
wherein R<1> represents an alkyl group of 1 to 3 carbon atoms, R<2> represents a hydrogen atom or an alkyl group of 1 to 3 carbon atoms and n denotes an integer of 1 to 3, with the proviso that when R<2> represents a hyrogen atom the 3-, 4- and 5-positions of the benzene ring are not simultaneously occupied by methoxy groups. These compounds can be formulated into pharmaceutical compositions for treating peptic ulcers.