发明名称 SUBSTITUTED BENZAZEPINES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 A group of 6,9-disubstituted-7,8-dihydroxy-1-phenyl- 2,3,4,5-tetrahydro-1H-3-benzazepine have dopaminergic activity. Examples of compounds of the invention are 9-chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-6-methyl- 2,3,4,5-tetrahydro-1H-3-benzazepine and 6,9-dichloro-7,8- dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3- benzazepine, preferably in the form of an acid addition salt thereof, have antihypertensive activity.
申请公布号 EP0004794(B1) 申请公布日期 1982.04.28
申请号 EP19790300601 申请日期 1979.04.11
申请人 SMITHKLINE BECKMAN CORPORATION 发明人 WEINSTOCK, JOSEPH
分类号 A61K31/55;A61P9/12;A61P25/00;A61P43/00;C07C41/26;C07C43/205;C07C43/225;C07C43/23;C07C45/63;C07C45/71;C07D223/16;C07D319/18;C07D491/04;(IPC1-7):07D223/16;61K31/55 主分类号 A61K31/55
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