发明名称 |
Tyrosylated proinsulin C-peptide derivatives |
摘要 |
The disclosed peptide derivative of the formula: Y-Tyr-Gly-R Wherein, Y represents a hydrogen atom or an amino protecting group, Tyr represents a tyrosine residue wherein at least one of the hydrogen atoms on the phenyl ring may be substituted by a radioactive iodine, Gly represents a glycine residue, and R represents a peptide residue corresponding to an amino acid sequence which includes at least positions 7 through 21 of human proinsulin C-peptide proves to be useful for determining C-peptide level in human serum.
|
申请公布号 |
US4327072(A) |
申请公布日期 |
1982.04.27 |
申请号 |
US19790097671 |
申请日期 |
1979.11.27 |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
INOUYE, KEN;KONO, MASAO;YOSHIDA, NOBUO;NAKAMURA, MASUHISA;OKABAYASHI, TADASHI;IGANO, KEN'ICHI |
分类号 |
G01N33/53;C07C67/00;C07C231/00;C07K14/00;C07K14/62;G01N33/534;G01N33/74;(IPC1-7):G01N33/56;A61K43/00;C07C103/52 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|