| 摘要 |
The invention relates to medicinally useful steroid derivatives, particularly amino-14 steroids substituted at the 17-position by a functional group represented by the general formula: <IMAGE> (I) wherein R1 is a hydroxy, hydroxyalkyl, alkoxy, acyloxy, carboxy or carbalkoxy group, or a hydrogen atom, and R2 is a hydroxy, alkoxy, or acyloxy group. These amino-14 steroids are prepared from the corresponding hydroxy-14 steroids, by the action of hydrazoic acid in the presence of boron trifluoride etherate to form the azido-14 derivative which is reduced.
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