| 摘要 |
L-isoleucine is prepared by cultivation of an analogue-resistant mutant of Brevibacterium thiogenitalis in an aqueous nutrient medium under aerobic conditions in the presence of from 0.001 to 15 w/v percent of a post-threonine precursor for L-isoleucine. The cultivation is preferably carried out at about 30 DEG C. and at a pH of 5 to 9. L-isoleucine is recovered from the fermentation broth. |
