| 摘要 |
<p>NEW MATERIAL:A compound shown by the formulaI(R<1> and R<2> are pyridyl, pyrimidyl, imidazolyl, 1,2,4-triazolyl, etc.; A is lower alkylene; R<3> is lower alkyl; l and m are 0, 1, or 2) and its salt. EXAMPLE:2-(2-Pyridyl) thio-1-(1-methyl-2-imidazolyl) thio-ethane. USE:An antiulcer and an antiphlogistic. PROCESS:For example, a compound shown by the formula 2 is reacted with a compound shown by the formula 3 (one of X<1> and X<2> is halogen, and the other is mercapto or group shown by the formula IV), to give a comound shown by the formula Ia. And, if necessary, this compound is oxidized or reduced, and converted into the desired compound shown by the formulaI. The compound shown by the formula III is novel, and, for example, obtained by reacting a compound shown by the formula R2-Y(Y is mercapro or group shown by the formula IV) with a compound shown by the formula Y<1>-A-Y<2>(Y<1> and Y<2> are halogen).</p> |
