| 摘要 |
<p>Ethers of Clavulanic Acid, A Process for their Preparation and Pharmaceutical Compositions containing them The compounds of the formula (I): (I) and salts and esters thereof (wherein R1 is a hydrogen atom or a methyl group; R2 is a hydrogen atom or a methyl group; and R3 is a hydrogen atom or a COR4, CO2R4 or CONR4R5 group where R4 is an alkyl group of up to 6 carbon atoms or a phenyl or benzyl group and R5 is a hydrogen atom or an alkyl group of up to six carbon atoms) possess .beta.-lactamase inhibitory properties, and give good blood levels and urinary recoveries after administration. The invention further provides a process for the preparation of these compounds, and pharmaceutical compositions containing them.</p> |
