摘要 |
A silylated silica or alumina covalently bonded to a chiral amino acid through a carboxyl group of said acid may be used as the solid stationary phase in the chromatographic resolution of racemic mixtures. Several classes of derivatives of such bound chiral amino acids also may be used in the resolution of racemates. Such derivatives include N-alkyl and N-acyl derivatives, and esters where the amino acid is a dicarboxylic acid or contains a hydroxy group.
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