发明名称 |
PYRIMIDONDERIVATER MED HISTAMIN H2-ANTAGONISTVIRKNING |
摘要 |
Compounds (1) …<CHEM>… in which… R<1> and R<2> are C1-C4 alkyl or together with the nitrogen atom to which they are attached form a pyrrolidino or piperidino group;… Y is methylene or sulphur;… X is methylene or oxygen provided that X is methylene when Y is sulphur;… Z is hydrogen or C1-C4 alkyl; and… R<5> is hydrogen, C1-4 alkyl or -A-B where… A is C1-C4 alkylene and… B is optionally substituted heteroaryl or phenyl are histamine H2-antagonists. Processes for their preparation and pharmaceutical compositions containing them are also described. |
申请公布号 |
DK435681(A) |
申请公布日期 |
1982.04.02 |
申请号 |
DK19810004356 |
申请日期 |
1981.10.01 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES |
发明人 |
COOPER D G;SACH G S |
分类号 |
C07D401/12;A61K31/505;A61P43/00;C07D213/38;C07D401/14;C07D405/14;C07D409/14;C07D417/14;C08B30/12;C13K1/06 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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