摘要 |
<p>Aspartic acid analogue suppresses the growth of the microorganism, but the suppression is lowered in the presence of aspartic acid. The microorganism is derived from such a stock as Brevibacterium divaricatum ATCC 14020, Bre. flavum ATCC 14067, Bre. lactofermentum ATCC 13869, Corynebacterium acetoacidophilum ATCC 13870, etc. by treating the stock with N-methyl-N'-nitro-N-nitroso guanidine-soln. (250 micro g/ml) at 30 deg. C for 30 min., and screening the stock having resistance to aspartic-acid analogues. The microorganism is cultivated in a medium contg. a C source e.g. glucose, sucrose, starch, organic acid, alcohol, etc. a N source, e.g. ammonium salt, ammonia gas, urea, etc. and other nutrients, at pH 5-9 at 24-37 deg.C for 2-7 days.</p> |