CEPHALOSPORIN COMPOUNDS

摘要

7-Acylamino cephalosporins compounds are described. They have the following formula wherein R is hydrogen or an acyl group of the formula R min -@- wherein R min is hydrogen, C1-C4 alkyl, or C1-C4 alxyl substituted by halogen or cyano; or R min is a group of the formula wherein R1 is phenoxy, phenylthio, phenyl, hydroxyphenyl, halophenyl, halo-substituted-hydroxyphenyl, or C1-C4 alkylphenyl, thienyl, furyl, or 2-aminothiazol-4-yl, a is hydrogen; b is hydrogen, hydroxy or amino, and a and b when taken together form an oximino group of the formula wherein R2 is hydrogen, C1-C4 alkyl or a group of the formula wherein R3 and R4 independently are hydrogen, C1-C4 alkyl, or R3 and R4 when taken together with the carbon atom to which they are attached form a four, five or six-membered carbocyclic ring;