发明名称 ANALGESIC
摘要 PURPOSE:An analgesic having low toxicity, comprising [6]-shogaol or [6]-gingerol, an extract from a ginger as an active ingredient. CONSTITUTION:A compound shown by the formula I (R is a group shown by the formula II or III) as an active ingredient is pharmaceutically manufactured into an injection, powder, tablet, etc. for use. The compound shown by the formula I can be obtained by extracting the rhizome of a ginger, a zingiberaceous plant with an ether, etc. to give an essence, fractionating it by column chromatography, followed by subjecting each fraction to thin layer chromatography so that it is separated. In case of oral administration, a dose is 70-500mg [6]-shogaol (a compound shown by the formula I where R is a group shown by the formula II) or about 140-200mg [6]-gingerol (a compound shown by the formula I where R is a group shown by the formula III).
申请公布号 JPS5746914(A) 申请公布日期 1982.03.17
申请号 JP19800122360 申请日期 1980.09.05
申请人 TSUMURA JIYUNTENDOU:KK 发明人 YUDA MASAKI;SUDOU KAZUHIKO;YUASA KAZUNORI;IKETANI YUKINOBU
分类号 A61K31/05;A61K31/12;A61K36/18;A61P25/04;C07C49/255 主分类号 A61K31/05
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