Pyrido[3,2-e]-as-triazines

摘要

The invention relates to new pyrido[3,2-e]-as-triazine derivatives of the formula I and pharmaceutically acceptable acid addition salts thereof, <IMAGE> I wherein R1 stands for a C1-20 alkyl-carbonyl group, halogen-C1-4 alkyl-carbonyl, benzoyl, phenyl-C1-4 alkyl-carbonyl, or pyridyl-carbonyl group; R2 is a hydrogen atom or a C1-4 alkyl-carbonyl group; or R1 and R2 form together with the adjacent nitrogen atoms a pyrazole-2,4-dione ring which carries a C1-6 alkyl substituent in position 3; R3 is a hydrogen atom, a C1-20 alkyl, phenyl, phenyl-C1-3 alkyl, furyl or pyridyl group or a phenyl group optionally substituted by one to three C1-4 alkoxy-groups. The compounds of the formula I are prepared by acylating the respective 1,2-un-substituted 1,2-dihydropyrido [3,2-e]-as-triazine derivatives. The new compounds exert valuable effects on the central nervous system and possess analgesic, antiphlogistic effects, and can be applied to advantage in therapy.