发明名称 |
PROCESS FOR THE PREPARATION OF SERINOL AND SERINOL DERIVATIVES |
摘要 |
A method for the synthesis of serinol and serinol derivatives substituted at the nitrogen atoms by reacting a lower 1,3-dialkoxy-isopropyl halide with ammonia or an amine to form a 1,3-dialkoxy-isopropylamine and then removing the ether groups by heating with a hydrogen halide acid. The method allows the production of serinol and serinol derivatives using inexpensive starting materials in a simple manner and obtaining a high purity product which is free of interfering isomers. Novel compounds obtained by the method which are useful as pharmaceutical intermediates, X-ray contrasting agents and cytostatic or psychopharmacological drugs are also disclosed. |
申请公布号 |
DE3060177(D1) |
申请公布日期 |
1982.03.11 |
申请号 |
DE19803060177 |
申请日期 |
1980.06.02 |
申请人 |
EPROVA AKTIENGESELLSCHAFT |
发明人 |
FELDER, ERNST, PROF. DR.;BIANCHI, SERGIO, DR.;BOLLINGER, HEINRICH, DR. |
分类号 |
C07C213/00;C07C67/00;C07C213/02;C07C215/10;C07D295/088;(IPC1-7):C07D295/08;C07C91/10;C07C89/02 |
主分类号 |
C07C213/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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