UN PROCEDIMIENTO PARA LA PREPARACION DE ESPIRO(CICLOHEXANO- 1,1'(3'H)-ISOBENZOFURANOS)

摘要

The present invention relates to novel spiro [cyclohexane-1,1 min (3 min H)- isobenzofuran]s of the formula …… wherein R1 is hydrogen; R2 is NR5R6 wherein R5 is hydrogen, loweralkyl; …… R6 is hydrogen or loweralkyl; R3 is hydrogen, loweralkyl or cycloalkyl having 3 to 7 carbon atoms, inclusive …… wherein X is hydrogen, halogen or loweralkyl; R is hydrogen, loweralkyl or hydroxy; R3 and R4 taken together with the carbon atom to which they are attached form a carbonyl group; the geometrical isomers and optical antipodes thereof and the pharmaceutically acceptable salts thereof wherein R5 is not the …… group, which compounds exhibit antidepressant, tranquilizer, analgesic and anticonvulsant activity.