摘要 |
1378381 Imidazoles BEECHAM GROUP Ltd 13 July 1972 [18 Aug 1971] 38716/71 Heading C2C The invention comprises novel compounds (I) wherein R and R 1 are each a hydrogen or halogen atom or a methoxycarbonyl, ethoxycarbonyl, carboxamido, nitro, trifluoromethyl, C 1-4 alkyl, hydroxyl, methoxyl, ethoxyl, benzyloxyl, acetoxyl, amino, methylamino, ethylamino, dimethylamino or acetamido group; R 2 is an amino or C 1-4 alkoxyl or benzyloxyl group; R 3 is a hydrogen atom or a C 1-7 hydrocarbon group; and R 4 is a hydrogen atom or a methyl group; or a tautomer, acid addition salt or hydrate thereof. They are made by standard methods. Pharmaceutical preparations showing antiinflammatory action contain (I) as active ingredient; administration may be orally, parenterally or by suppository. |