发明名称 PROCEDEU PENTRU PREPARAREA UNOR NOI DERIVATI AI XANTINEI
摘要 <p>Compounds of the formula <IMAGE> wherein R is methyl or ethyl, R1 is methyl, ethyl or <IMAGE> and R2 is methyl, ethyl, <IMAGE> <IMAGE> <IMAGE> where Alk is alkyl of 1 to 4 carbon atoms, Q is ethyl, propyl, isopropyl or 2-hydroxy-propyl, A is 3-phenoxy-2-hydroxy-propyl, where the phenyl ring is substituted in the o-position by hydroxy, methoxy, n-hexyloxy or benzyloxy, B is alkyl of 1 to 4 carbon atoms, phenyl, p-methyl-phenyl, 3-phenyl-3-hydroxy-isopropyl or A, as defined above, and N IS AN INTEGER FROM 2 TO 6, INCLUSIVE, PROVIDED, HOWEVER, THAT ONE OF R1 and R2 must be methyl or ethyl and the other has one of the other respective meanings indicated; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as peripheral vasodilators.</p>
申请公布号 RO68381(A) 申请公布日期 1982.02.26
申请号 RO19750084245 申请日期 1975.12.18
申请人 CH BOEHRINGER SOHN,DE 发明人 KONZ,WILHELM,DE;REICHL,RICHARD,DE
分类号 A61K31/522;C07D473/06;C07D473/08;C07D473/10;(IPC1-7):07D473/12 主分类号 A61K31/522
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