发明名称 IMPROVEMENTS IN OR RELATING TO ANTIBIOTICS
摘要 7β-acylamidoceph-3-em-4-carboxylic acids and 6β-acylamidopenam-3-carboxylic acid, and their alk. salts or acid salts, esters and sulfoxides with antibacterial activity and high stability to β-lactamase, were synthesized. 7-aminoceph-3-em-4-carboxylic acid or 6-aminopenam-3-carboxylic acid was related with acylating agent at -20-20≦̸C in the inactive inog. solvent to give syn- or anti- isomer, or the mixt. contg. more than 75% one isomer.
申请公布号 ZA7200568(B) 申请公布日期 1972.10.25
申请号 ZA19720000568 申请日期 1972.01.28
申请人 GLAXO LABOR LTD 发明人 GREGSON M;COOK M;GREGORY G
分类号 A61K;C07D499/64;C07D501/22;C07D501/24 主分类号 A61K
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