发明名称 BETA-LACTAM ANTIBACTERIAL AGENTS, THEIR PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR THEIR PREPARATION
摘要 The compounds of the formula (I): <IMAGE> (I) wherein R1 is a hydrogen atom, a trityl group or an acyl group as found in known antibacterially active penicillins or cephalosporins; R2 is a hydrogen atom, a lower alkyl group or an aryl group; R3 is a hydrogen atom, a lower alkyl group, a substituted lower alkyl or a thiosubstituted lower alkyl group; and R4 is a group such that CO2R4 is a carboxylic acid group or a salt or readily removable ester thereof; are antibiotics. The compounds may be formulated in pharmaceutical compositions. Processes for the preparation of the compounds (I) are also described.
申请公布号 DE2961633(D1) 申请公布日期 1982.02.18
申请号 DE19792961633 申请日期 1979.02.15
申请人 BEECHAM GROUP PLC 发明人 PEARSON, MICHAEL JOHN
分类号 A61K31/505;A61P31/04;C07D205/085;C07D205/095;C07D487/14;(IPC1-7):C07D487/14;A61K31/50 主分类号 A61K31/505
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