Procédé de préparation d'un inhibiteur d'enzyme

摘要

1346318 Peptidates E R SQUIBB & SONS Inc 19 April 1971 [18 March 1970 6 Aug 1970] 35665/73 Divided out of 1346317 Heading C2C The novel peptides (R) n -G-ile-pro-pro-Y (R)n-pro-G-ile-pro-pro-Y (R) n -F-pro-G-ile-pro-pro-Y (R) n -pro-F-pro-G-ile-pro-pro-Y (R) n -arg-pro-F-pro-G-ile-pro-pro-Y (R) n -pro-arg-pro-F-pro-G-ile-pro-pro-Y (R) n -trp-pro-arg-pro-F-pro-G-ile-pro-pro-Y and (R) n -pyroglu-trp-pro-arg-pro-F-pro-Y in which R is an N-terminal protecting group, n is 0 or 1, F is threanyl or glycyl, G is glutamyl or glutaminyl and Y is OH or a carboxyl protecting group are prepared by conventional solid phase methods used in peptide syntheses.