发明名称 CYCLIC IMINO ACID HAVING ACTIVITY CAPABLE OF INHIBITING MUTATION AND ITS PREPARATION
摘要 NEW MATERIAL:A cyclic imino acid shown by the formula I (n is 2 or 3). Colorless needlelike crystal; browning and decomposing gradually at >=160 deg.C, not melting, soluble in water, slightly soluble in organic solvents; color reaction, positive in ninhydrin reaction, Rydon and Smith reaction, and tetrazolium reaction; decoloring potassium permanganate. EXAMPLE:5-cyanophlorin shown by the formula II. USE:A substance capable of inhibiting mutation of bacteria, and preventive for carcinogenicity. (Preventing the tumorigenesis of chick fetal fibroblast caused by chick inner tumor). PROCESS:''Favolus brasiliensis''(Fr.)Fr. K2013 (FERM-P5458), cyclic imino acid producing bacterium belonging to the genus ''Favolus'', is cultivated aerobically and a compound shown by the formula I is collected from the culture.
申请公布号 JPS5724358(A) 申请公布日期 1982.02.08
申请号 JP19800099083 申请日期 1980.07.18
申请人 MICROBIAL CHEM RES FOUND 发明人 UMEZAWA HAMAO;TAKEUCHI TOMIO;TANABE OSAMU;IINUMA HIRONOBU
分类号 C12P17/12;A61K31/40;A61K31/445;A61P35/00;C07D207/00;C07D207/16;C07D221/00;C07D221/02;C12P17/10;C12R1/645 主分类号 C12P17/12
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