| 摘要 |
The patent is concerned with a new compound which is 1-methyl-2-(3'-sulphenyl-4'-chlorobenzamido)-isoindoline of formula: <IMAGE> This compound, which is endowed with diuretic, salutaric and hypotensive activity, is prepared: (a) reacting alpha -methyl- alpha , alpha '-dibromo-o.xylene with t.butylcarbazate, (b) decomposing the thus obtained 1-methyl-N-(t.butyloxycarbonylamine)-isoindoline to the corresponding amino compound, (c) reacting the 1-methyl-2-amino-isoindoline hydrochloride with a halide of 4-chloro-sulphamido benzoic acid. |
