摘要 |
Novel 1,2,4-triazole derivatives are described having the following formula <CHEM> wherein R represents hydrogen or methyl, R1 stands for hydrogen or (C1-C4)alkyl, or R and R1 taken together may represent a further bond between the carbon atom and the oxygen atom, R2 and R4 each independently, represent hydrogen, chloro, fluoro, bromo, (C1-C4)alkyl or (C1-C4)alkoxy, R3 stands for (C1-C4)alkyl, (C1-C4)alkoxy, allyloxy propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R3 and R4 taken together may represent a methylenedioxy group. Also described is a process for their manufacture. Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredient are also claimed. |