发明名称 |
ORNITHINE AND ARGININE SALTS OF BRANCHED CHAIN KETO ACIDS AND USES IN TREATMENT OF HEPATIC AND RENAL DISORDERS |
摘要 |
<p>Novel compounds are prepared by reacting ornithine or arginine with alpha keto analogs of branched chain essential amino acids, namely valine, leucine and isoleucine. The compounds are useful either individually or as a mixture in the treatment of hepatic disorders which are characterized by hyperammonemia and portal systemic encephalopathy. Use of these compounds in treatment of renal failure also appears promising.</p> |
申请公布号 |
CA1115729(A) |
申请公布日期 |
1982.01.05 |
申请号 |
CA19790323574 |
申请日期 |
1979.03.16 |
申请人 |
JOHNS HOPKINS UNIVERSITY (THE) |
发明人 |
WALSER, MACKENZIE |
分类号 |
A61K31/195;A61K31/19;A61K31/198;A61P1/00;A61P1/16;A61P13/02;A61P15/00;C07C59/185;C07C67/00;C07C227/00;C07C229/26;C07C239/00;C07C279/14;(IPC1-7):07C101/24 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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