发明名称 PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE FENIL ALCOXI PROPANOLAMINAS
摘要 <p>1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE Novel derivatives of phenyl alcoxy propanol amines having the general formula I : see diagramm : EP0037781,P13,F1 in which : X represents a hydrogen atom, a lower alkyl radical and more particularly the methyl radical, a lower alcoxy radical and more particularly the methoxy radical, n represents the values 1 - 3, and R represents an isopropyl or terbutyl radical, such that their salts with mineral or organic acids are therapeutically acceptable. 1. Claims for the Contracting State : AT Process for preparing compounds of the general formula I : see diagramm : EP0037781,P14,F1 in which : X represents a hydrogen atom, a lower alkyl radical and more particularly the methyl radical, a lower alcoxy radical and more particularly the methoxy radical, n represents the values 1 - 3, and R represents an isopropyl or terbutyl radical, such that their salts with mineral or organic acids are therapeutically acceptable, characterised in that a glycidyl ether of the formula II : see diagramm : EP0037781,P14,F2 in which X and n have the significations given above, is reacted in a solvent medium, in particular an alcohol such as methanol, on a primary amine of the formula III : R-NH2 in which R has the signification given previously.</p>
申请公布号 ES500821(D0) 申请公布日期 1982.01.01
申请号 ES19210005008 申请日期 1981.03.28
申请人 PIERRE FABRE S.A. 发明人
分类号 C07D303/22;(IPC1-7):07C93/08;61K31/135 主分类号 C07D303/22
代理机构 代理人
主权项
地址
您可能感兴趣的专利