发明名称 |
1,6-Naphthyridine derivatives, and antidinic and cerebral circulation improver containing such derivatives |
摘要 |
This invention relates to the novel 1,6-naphthyridine derivatives useful as antidinic and/or cerebral circulation improver, such novel derivatives being represented by the following general formula: <IMAGE> (I) (wherein R is a C2-10 alkyl which may have hydroxyl, lower alkylcarbonyl, lower alkyloxycarbonyl or phenoxy as a substituent; a C2-10 unsaturated aliphatic hydrocarbon group having unsaturated double bond(s); a phenyl-lower alkyl which may have halogen, lower alkyl, lower alkoxy or lower alkylthio as substituent(s) attached to the phenyl ring; a cinnamyl which may have halogen, nitro, lower alkyl or lower alkoxy as substituent(s) attached to the phenyl ring; propargyl; 1-naphthylmethyl; 2-thenyl; cyclohexenyl; a cycloalkyl-lower alkyl with a 3- to 6-membered ring; 1/2(C2-4 alkylene); 1/2(butenylene), or diphenylmethyl, and in case two alkoxyl groups are present attached to the phenyl ring, they may be bonded to form a ring) and salt thereof.
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申请公布号 |
US4308273(A) |
申请公布日期 |
1981.12.29 |
申请号 |
US19790083556 |
申请日期 |
1979.10.10 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
YAMANAKA, HIROSHI;SAKAMOTO, TAKAO;SHIOZAWA, AKIRA;ICHIKAWA, YUH-ICHIRO;ISHIKAWA, MICHIO;MIYAZAKI, HIROSHI |
分类号 |
A61K31/435;A61P27/16;C07D471/04;(IPC1-7):A61K31/43 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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地址 |
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