发明名称 1,6-Naphthyridine derivatives, and antidinic and cerebral circulation improver containing such derivatives
摘要 This invention relates to the novel 1,6-naphthyridine derivatives useful as antidinic and/or cerebral circulation improver, such novel derivatives being represented by the following general formula: <IMAGE> (I) (wherein R is a C2-10 alkyl which may have hydroxyl, lower alkylcarbonyl, lower alkyloxycarbonyl or phenoxy as a substituent; a C2-10 unsaturated aliphatic hydrocarbon group having unsaturated double bond(s); a phenyl-lower alkyl which may have halogen, lower alkyl, lower alkoxy or lower alkylthio as substituent(s) attached to the phenyl ring; a cinnamyl which may have halogen, nitro, lower alkyl or lower alkoxy as substituent(s) attached to the phenyl ring; propargyl; 1-naphthylmethyl; 2-thenyl; cyclohexenyl; a cycloalkyl-lower alkyl with a 3- to 6-membered ring; 1/2(C2-4 alkylene); 1/2(butenylene), or diphenylmethyl, and in case two alkoxyl groups are present attached to the phenyl ring, they may be bonded to form a ring) and salt thereof.
申请公布号 US4308273(A) 申请公布日期 1981.12.29
申请号 US19790083556 申请日期 1979.10.10
申请人 NIPPON KAYAKU KABUSHIKI KAISHA 发明人 YAMANAKA, HIROSHI;SAKAMOTO, TAKAO;SHIOZAWA, AKIRA;ICHIKAWA, YUH-ICHIRO;ISHIKAWA, MICHIO;MIYAZAKI, HIROSHI
分类号 A61K31/435;A61P27/16;C07D471/04;(IPC1-7):A61K31/43 主分类号 A61K31/435
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