| 发明名称 |
COMPOUNDS FOR MODIFYING DRUG RESISTANCE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
| 摘要 |
The present invention relates to novel compounds of formula (I) which maintain, increase, or restore sensitivity of cells to therapeutic or prophylactic agents. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for treatment of multi-drug resistant cells, for prevention of the development of multi-drug resistance and for use in multi-drug resistant cancer therapy. |
| 申请公布号 |
IL107109(D0) |
申请公布日期 |
1993.12.28 |
| 申请号 |
IL19930107109 |
申请日期 |
1993.09.26 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
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| 分类号 |
C07D211/60;A61K31/38;A61K31/395;A61K31/40;A61K31/4025;A61K31/4427;A61K31/4433;A61K31/445;A61K31/452;A61K31/4523;A61K31/52;A61P35/00;C07D207/16;C07D235/00;C07D239/00;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D409/12;C07D471/04;C07D473/00;C07D487/04;(IPC1-7):C07D/ |
主分类号 |
C07D211/60 |
| 代理机构 |
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