发明名称 |
Assay for N-terminal type I collagen telopeptide that survives bone resorption in vivo |
摘要 |
A method for assaying bone resorption rates which consists of quantitating the concentration of peptide fragments derived from bone collagen, found in a body fluid is disclosed. The method includes immunometric assay, fluorometric assay and electrochemical titration. The structure of specific peptide fragments having 3-hydroxypyridinium cross-links found in urine of Paget's disease patients and procedures for making monoclonal antibodies is described.
|
申请公布号 |
US5607862(A) |
申请公布日期 |
1997.03.04 |
申请号 |
US19950497731 |
申请日期 |
1995.06.21 |
申请人 |
WASHINGTON RESEARCH FOUNDATION |
发明人 |
EYRE, DAVID R. |
分类号 |
G01N33/50;A61K38/00;C07K1/113;C07K1/20;C07K7/02;C07K7/06;C07K7/08;C07K14/00;C07K14/78;C07K16/00;C07K16/18;C07K19/00;C09H1/00;C12N5/00;C12N5/06;C12N5/10;C12N5/20;C12N15/00;C12N15/02;C12P21/08;C12Q1/00;C12R1/91;G01N33/53;G01N33/577;G01N33/68;(IPC1-7):G01N33/53 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|