| 摘要 |
D-Homosteroids with endocrine activity and the formula <IMAGE> in which the dotted bond in the C ring is optional; R<18> is hydrogen or methyl; R<17a beta > is hydrogen, acyl, lower alkyl, cycloalkyl-lower-alkyl; benzyl, furfuryl or tetrahydropyranyl and R<17a alpha > is hydrogen, lower alkyl, ethynyl, vinyl, allyl, methallyl, propadienyl, 1-propynyl, butadiynyl or chloroethynyl, are prepared. They can be obtained by isomerisation or dehydrogenation and isomerisation of a corresponding D-homosteroid-5(10), 9(11), 16-triene. Resulting compounds of the formula I in which R<17a beta > is hydrogen can be acylated, and those in which R<17a beta > is acyl can be hydrolysed.
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