| 摘要 |
<p>Novel steroids, which can be used as antiinflammatory agents, have the formula or the 1,2-dehydro derivative thereof, wherein X is -S-, , or ; R1 is alkyl, aryl or acyloxyalkyl; R2 is fluoro, chloro, bromo, or iodo; R3 is hydrogen, fluoro, chloro, bromo or iodo; R4 is carbonyl, .beta.-hydroxymethyl-ene or .beta.-acyloxymethylene; and R5 is hydrogen or fluoro; wherein the term "aryl" is phenyl or phenyl substituted with 1 or 2 alkyl, alkoxy, fluoro, chloro, bromo, or iodo groups; the terms "alkyl" and "alkoxy" refer to groups having 1 to 10 carbon atoms; and the term "acyloxy" refers to groups of the formula wherein Y is alkyl or aryl.</p> |
