发明名称 FAS LIGAND-LIKE PROTEIN, ITS PRODUCTION AND USE
摘要 This invention relates to a Fas ligand-like protein having an apoptosisinducing activity, etc. or its salt, a partial peptide of the protein or its salt; a DNA coding for the protein; a recombinant vector; a transformant; a method for producing the protein, a pharmaceutical composition comprising the protein, the partial peptide or its salt; and an antibody to the protein or the partial peptide. The protein, the partial peptide or its salt, and the DNA are useful as a prophylactic or therapeutic agent for cancer, viral infection, Helicobacter pylori infection, invasive staphylococcia, hepatitis, nephritis, bone disease, atherosclerosis or pain. The antibody can be used in assay of the protein, the partial peptide or its salt. The protein, the partial peptide or its salt is useful as a reagent for the screening for candidate medical compounds.
申请公布号 CA2260767(A1) 申请公布日期 1998.01.29
申请号 CA19972260767 申请日期 1997.07.17
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 SHINTANI, YASUSHI;NISHI, KAZUNORI;HIKICHI, YUKIKO
分类号 A61K38/00;A61K48/00;C07K14/47;C07K14/705;C12N15/12;(IPC1-7):C12N15/19;A01K67/027;C12N5/10;A61K38/19;C07K16/24;C07K14/52;G01N33/566;C12Q1/68;A61K31/70 主分类号 A61K38/00
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