发明名称 Biologically-active tricyclic amines, methods for their preparation and pharmaceutical compositions containing same.
摘要 <p>Compounds having the general formula &lt;CHEM&gt; or an acid addition salt thereof, whereby the substituent -(CH2)m-NR1R2 is present at one of the positions a, b or c, X and Y each represent hydrogen, alkyl (1-6 C), alkoxy (1-6C), halogen, hydroxy, acyloxy, or both X and Y at vinical positions may also represent a methylene dioxy group, R1 and R2 represent hydrogen or alkyl (1-6 C) or R1 + R2 together with the nitrogen represent a heterocyclic 5- or 6-ring which, optionally may contain a second nitrogen atom or an oxygen atom, and m represents the number 0 or 1, having valuable CNS and cardiovascular properties. </p>
申请公布号 EP0041293(A1) 申请公布日期 1981.12.09
申请号 EP19810200545 申请日期 1981.05.21
申请人 AKZO N.V. 发明人 WIERINGA, JOHANNES HUBERTUS, DR.;VAN DER VLUGT, FRANS ABRAHAM, DR.
分类号 C07C215/64;C07C67/00;C07C209/00;C07C209/24;C07C209/40;C07C209/50;C07C209/56;C07C213/00;C07C217/74;C07C219/28;C07D233/58;C07D295/08;C07D295/096;C07D295/185;C07D521/00;(IPC1-7):07C93/14;61K31/13;07C93/26;07C87/458;07C91/28;07D295/08 主分类号 C07C215/64
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