METHODS FOR TREATMENT OF DIABETES USING PEPTIDE ANALOGUES OF INSULIN
摘要
The present invention is directed toward peptide analogues of insulin (B) chain that are generally derived from peptides comprising residues (9 to 23) of the native (B) chain sequence. The analogues are altered from the native sequence at position (12, 13, 15) and/or (16), and may be additionally altered at position (19) and/or other positions. Pharmaceutical compositions containing these peptide analogues are provided. The peptide analogues are useful for treating and inhibiting the development of diabetes.
申请公布号
WO9942482(A1)
申请公布日期
1999.08.26
申请号
WO1999US03915
申请日期
1999.02.23
申请人
NEUROCRINE BIOSCIENCES, INC.;GAUR, AMITABH;LING, NICHOLAS;CONLON, PAUL, J.