Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions.

摘要

Compounds of formula (II):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="30" wi="75" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>or a pharmaceutically acceptable salt, lower alkyl or aralkyl ester or amide thereof, wherein R<Sup>1</Sup> and R<Sup>2</Sup>, which may be the same or different, are each a hydrogen atom or a methyl group, n is 1, 2 or 3, and Z is a C<Sub>1-6</Sub> alkyl or C<Sub>1-6</Sub> alkoxy group, or a halogen or hydrogen atom, are useful in treating obesity and/or hyperglycaemia and/or inflammation in mammals.