发明名称 |
Immunity to trypanosomatids species |
摘要 |
The present invention relates to trypanosomatid histones in substantially isolated form for use as a protective antigen against trypanosomatic infection. These histones may be either isolated from the corresponding parasite or be produced by means of recombinant DNA techniques. For the latter purpose the invention also provides genes encoding histones and derivatives of the genes like other nucleic acids and gene products like peptides and proteins. The invention further provides diagnostic tests, pharmaceutical compositions and vaccines comprising the usual excipients and/or adjuvants and at least one histone, a histone encoding gene or a derivative thereof. |
申请公布号 |
AU733720(B2) |
申请公布日期 |
2001.05.24 |
申请号 |
AU19970020272 |
申请日期 |
1997.03.12 |
申请人 |
SOVAREC S.A. |
发明人 |
NICOLAS JOSEPH FASEL;THERESA ANN GLASER |
分类号 |
C12N15/09;A61K31/00;A61K31/70;A61K31/7088;A61K38/00;A61K39/00;A61K39/005;A61K39/008;A61K39/395;A61K45/00;A61K48/00;A61P33/00;A61P33/02;C07K14/20;C07K14/44;C07K16/20;C07K16/44;C12N1/21;C12N15/30;C12N15/70;C12Q1/68;G01N33/50;G01N33/569 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|