发明名称 IMPROVED ANTI-INFLAMMATORY COMBINATION HAVING REDUCED ULCEROGENICITY
摘要 A novel drug combination for more effective treatment of pain, fever, and inflammation with reduced ulcerogenicity comprising (a) 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid (indomethacin), and (b) a member selected from phenyl benzoic acid compounds, especially 2-hydroxy-5-(2',4'-difluorophenyl)benzoic acid (diflunisal), wherein the molar ratio of (b) to (a) is from 0.5 to 1.0 to 15.0 to 1.0.
申请公布号 ZA8001821(B) 申请公布日期 1981.11.25
申请号 ZA19800001821 申请日期 1980.03.27
申请人 MERCK & CO INC 发明人 TSUNG YING SHEN
分类号 A61K31/40;A61K;A61K31/105;A61K31/165;A61K31/19;A61K31/235;A61K31/405;A61K31/42;A61K31/44;A61P25/04;A61P29/00;C07C;C07C57/58;C07C59/64;C07C65/05;C07D209/28 主分类号 A61K31/40
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